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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/10761/4050
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Data: | 16-mar-2018 |
Autori: | Sciuto, Emanuele Luigi |
Titolo: | Development of Innovative Technologies for DNA Extraction and Detection |
Abstract: | The Ph.D. project has been focused on the development of fast, multiplex, innovative and easy-to-use technological platforms for DNA analysis (from extraction to detection), implemented into portable and miniaturized devices. These types of technologies are called Point-of-Care (PoC) and could create the conditions for a more efficient clinical analysis, introducing a series of advantages:
Fast and cheap procedures for biological samples preparation and analysis
Fast diagnosis
Identification and analysis of different DNA mutations (complex phenotypes and drug-resistance related)
Disease-specific and therapy-specific pattern definition
My research activity has been divided into three main parts, which will be described in the subsequent chapters:
1. Development and characterization of a miniaturized platform for DNA extraction.
2. Development and characterization of miniaturized systems for DNA detection with both optical transduction methods (via RT-PCR) and electrical methods (electrochemical detection).
3. Development of molecular methods for the detection of environmental analytes. |
In | Area 02 - Scienze fisiche
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